Authors
Keshav Raghuvanshi, Daniel Zell, Lutz Ackermann
Publication date
2017/2/24
Journal
Organic Letters
Volume
19
Issue
6
Pages
1278-1281
Publisher
American Chemical Society
Description
C–H oxygenations of synthetically meaningful sulfoximine benzamides were accomplished by a versatile ruthenium catalysis regime. The ruthenium(II) catalyst was characterized by excellent mono- and chemoselectivity as well as positional selectivity via facile base-assisted intramolecular electrophilic substitution-type (BIES) C–H activation. The synthetic utility of the approach was reflected by high functional group tolerance and sulfoximine removal in a traceless fashion.
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