Authors
Keshav Raghuvanshi, Karsten Rauch, Lutz Ackermann
Publication date
2015/1/19
Journal
Chemistry-A European Journal
Volume
21
Issue
4
Pages
1790-1794
Publisher
WILEY‐VCH Verlag
Description
Intermolecular CH acyloxylations of phenols with removable directing groups were accomplished with a versatile ruthenium catalyst. Specifically, a cationic ruthenium(II) complex, formed in situ, enabled the chemoselective CH oxygenations of a broad range of substrates. The catalyst proved tolerant of synthetically valuable functional groups, and the substrate scope included both (hetero)aromatic and, the more challenging, aliphatic carboxylic acids. The proposed reaction mechanism involves a reversible CH ruthenation and an oxidatively induced CO‐bond‐forming reductive elimination.
Scholar articles
K Raghuvanshi, K Rauch, L Ackermann - Chemistry–A European Journal, 2015