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The paper presents the results of an experimental campaign aimed at investigating the in-plane and out-of-plane behavior of tuff and fired clay brick masonry panels reinforced by a commercial, not yet tested, Textile Reinforced Mortar (TRM) system. The TRM, consisting of hydraulic lime mortar coupled with a bidirectional glass fabric (total thickness of 30 mm), was applied on both sides of the panels and connected through stainless-steel helical bars. First, a mechanical characterization of the TRM system was carried out, according to recent guidelines (AC434 and CNR-DT215) by means of tensile tests and single-shear bond tests on the two different substrates. Then, the effectiveness of the reinforcement was investigated through uniaxial compression, diagonal compression and three-point bending tests on masonry panels. After that, experimental results were compared to the predictions of recent guidelines and …