Authors
Uwe Gneveckow, Andreas Jordan, Regina Scholz, Volker Brüß, Norbert Waldöfner, Jens Ricke, Annelie Feussner, Bert Hildebrandt, Beate Rau, Peter Wust
Publication date
2004/6
Journal
Medical physics
Volume
31
Issue
6
Pages
1444-1451
Publisher
American Association of Physicists in Medicine
Description
Magnetic fluid hyperthermia (MFH) is a new approach to deposit heat power in deep tissues by overcoming limitations of conventional heat treatments. After infiltration of the target tissue with nanosized magnetic particles, the power of an alternating magnetic field is transformed into heat. The combination of the 100 kHz magnetic field applicator and the magnetofluid (MF), which both are designed for medical use, is investigated with respect to its dosage recommendations and clinical applicability. We found a magnetic field strength of up to 18 kA/m in a cylindrical treatment area of 20 cm diameter and aperture height up to 300 mm. The specific absorption rate (SAR) can be controlled directly by the magnetic field strength during the treatment. The relationship between magnetic field strength and the iron normalized SAR is only slightly depending on the concentration of the MF and can be used for planning the …
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