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Regions affected by resource scarcity, poverty, and land-use conflicts need to advocate the merits of practices strongly grounded in sustainable land management. This review paper provides an analysis of agroforestry as an integrated system embedded in complex relations between resource uses in the Water–Energy–Land–Food (WELF) nexus. Using the African Sahel region as a case study, the paper explains the need for understanding land management practices, such as agroforestry, through the lens of trade-offs and benefits inherent in the WELF nexus. Agroforestry practices are demonstrated to be valuable interventions leading to i) resilience to climate stresses, ii) water, energy, and food securities, iii) mitigation of resource-oriented harbingers of conflicts and iv) development opportunities. These goals can also yield valuable results in terms of promoting sustainable development, i.e. functional …