Authors
Cristiane Gurgel Lin, Laurel Anne Schaider, Daniel Joseph Brabander, Alan David Woolf
Publication date
2010/4/1
Journal
Pediatrics
Volume
125
Issue
4
Pages
e828-e835
Publisher
American Academy of Pediatrics
Description
BACKGROUND
Significant lead poisoning has been associated with imported nonpaint products.
OBJECTIVES
To describe cases of pediatric lead intoxication from imported Indian spices and cultural powders, determine lead concentrations in these products, and predict effects of ingestion on pediatric blood lead levels (BLLs).
PATIENTS AND METHODS
Cases and case-study information were obtained from patients followed by the Pediatric Environmental Health Center (Children's Hospital Boston). Imported spices (n = 86) and cultural powders (n = 71) were analyzed for lead by using x-ray fluorescence spectroscopy. The simple bioaccessibility extraction test was used to estimate oral bioavailability. The integrated exposure uptake biokinetic model for lead in children was used to predict population-wide geometric mean BLLs and the probability of elevated …
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