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Large parts of Central Asia are characterized by a semiarid to arid climate. Therefore, areas close to shallow groundwater, rivers and lakes are characterized by unique water-dependent ecosystems and human societies which have developed over millennia in close interaction with the naturally limited water resources. In the early 21st century, global climate change, population growth, river damming, large-scale water abstractions and rising levels of pollution exert multiple pressures on the region’s water resources, aquatic and terrestrial ecosystems at historically high levels. Water scarcity threatens the livelihood of populations locally and in transboundary settings by a growing competition over a limited resource. This context is of particular importance since all major rivers of the region cross at least one international border. The complexity and character of water-related challenges in the region mean that …