Authors
Eren Yüncü, Ulaş Işıldak, Matthew P Williams, Christian D Huber, Olga Flegontova, Leonid A Vyazov, Piya Changmai, Pavel Flegontov
Publication date
2023/4/28
Journal
bioRxiv
Pages
2023.04. 25.538339
Publisher
Cold Spring Harbor Laboratory
Description
Although a broad range of methods exists for reconstructing population history from genome-wide single nucleotide polymorphism data, just a few methods gained popularity in archaeogenetics: principal component analysis (PCA); ADMIXTURE, an algorithm that models individuals as mixtures of multiple ancestral sources represented by actual or inferred populations; formal tests for admixture such as f 3-statistics and D/f 4-statistics; and qpAdm, a tool for fitting two-component and more complex admixture models to groups or individuals. Despite their popularity in archaeogenetics, which is explained by modest computational requirements and ability to analyze data of various types and qualities, protocols relying on qpAdm that screen numerous alternative models of varying complexity and find “fitting” models (often considering both estimated admixture proportions and p-values as a composite criterion of model …
Total citations
2023202422
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