Authors
Amnon Cohen, Attilio Rovelli, Domenico Franco Merlo, Maria Teresa van Lint, Edoardo Lanino, Dorine Bresters, Marcello Ceppi, Vittorio Bocchini, André Tichelli, Gerard Socié
Publication date
2007/6/10
Journal
Journal of clinical Oncology
Volume
25
Issue
17
Pages
2449-2454
Publisher
American Society of Clinical Oncology
Description
Purpose
The effects of hematopoietic stem-cell transplantation (HSCT) on thyroid carcinogenesis needs to be determined in a large population. This study evaluates the incidence and the risk factors contributing to secondary thyroid carcinoma (STC) in patients who receive transplantation.
Patients and Methods
We performed a retrospective investigational study, comparing data obtained by means of a two-step questionnaire from the 166 centers who replied, and data reported to the European Group for Blood and Marrow Transplantation (EBMT) registry on their transplantation activity. During the follow-up period (1985 to 2003), 32 instances of STC were found within the EBMT cohort of 68,936 patients who received transplants. These patients were then compared with age- and sex-specific incidence rates in the European population and risk factors for STC were analyzed …
Total citations
Scholar articles
A Cohen, A Rovelli, DF Merlo, MT van Lint, E Lanino… - Journal of clinical Oncology, 2007