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Interfaces are good traps for implanted He, but are also susceptible to He-induced embrittlement. Better understanding of the mechanisms of He interactions with interfaces may enable design of interfaces that control He while remaining mechanically sound. We review recent work that aims to gain such insight by determining how interface structure influences He trapping and the equation of state of He in interface bubbles as well as how He-induced hardening depends on interface area per unit volume in composite materials.