Authors
Muhd Hanis Md Idris, Siti Balkis Budin, Mohamad Osman, Jamaludin Mohamed
Publication date
2012
Journal
Excli Journal
Volume
11
Pages
659
Publisher
Leibniz Research Centre for Working Environment and Human Factors
Description
Diabetes mellitus contributes to male sexual dysfunction and infertility by modulating oxidative damage. To date, a number of studies have demonstrated antioxidant properties of Hibiscus sabdariffa Linn. This study was designed to investigate the effects of H. sabdariffa UKMR-2 variety on sperm functioning of streptozotocin-induced diabetic rats. Male Sprague-Dawley rats were allotted into four groups, namely control group (C), H. sabdariffa extract (HSE) group, diabetes group (D) and diabetes plus HSE group (D+ HSE). HSE (100 mg/kg/body weight) was administered orally for 28 consecutive days. After 28-days of supplementation, the rats were sacrificed to obtain epididymal sperm. Administration of HSE significantly lowered the level of fasting blood glucose and increased plasma insulin level in D+ HSE group as compared to D group (p< 0.05). Sperm quality in the D+ HSE group was improved with …
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