Authors
Amy Zipursky, Nathan Kuppermann, Yaron Finkelstein, Roger Zemek, Amy C Plint, Franz E Babl, Stuart R Dalziel, Stephen B Freedman, Dale W Steele, Ricardo M Fernandes, Todd A Florin, Derek Stephens, Anupam Kharbanda, Damian Roland, Mark D Lyttle, David W Johnson, David Schnadower, Charles G Macias, Javier Benito, Suzanne Schuh
Publication date
2020/8/1
Journal
Pediatrics
Volume
146
Issue
2
Publisher
American Academy of Pediatrics
Description
METHODS:
We analyzed a retrospective cohort study of previously healthy infants aged 2 to 12 months with bronchiolitis. Variables examined included network, poor feeding, dehydration, nasal flaring, chest retractions, apnea, saturation, respiratory rate, fever, and suspected bacterial infection. Outcomes included systemic antibiotic administration and urine, blood, or viral testing or chest radiography (CXR).
RESULTS:
In total, 180 of 2359 (7.6%) infants received antibiotics, ranging from 3.5% in the United Kingdom and Ireland to 11.1% in the United States. CXR (adjusted odds ratio [aOR] 2.3; 95% confidence interval 1.6–3.2), apnea (aOR 2.2; 1.1–3.5), and fever (aOR 2.4; 1.7–3.4) were associated with antibiotic use, which did not vary across networks (P=. 15). In total, 768 of 2359 infants (32.6%) had≥ 1 nonindicated test, ranging from 12.7% in the United Kingdom and Ireland to 50% in Spain and Portugal …
Scholar articles
A Zipursky, N Kuppermann, Y Finkelstein, R Zemek… - Pediatrics, 2020