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Quantum materials with pyrochlore structures harbor a plethora of exotic electronic phases, such as magnetic Weyl semimetal, spin ice, and quantum spin liquid. An interface between two dissimilar pyrochlore compounds can feature a strong interplay between distinct many-body phases, supporting emergent interfacial phenomena. In this presentation, we report on the evidence for the emergence of electronic nematicity at the interface of rare-earth iridates and titanates pyrochlores. We will unveil experimental signatures for the unusual coupling between non-trivial band topology, electronic correlations, and geometrical frustration. Additionally, we will compare our system to other correlated topological materials with similar electronic nematicity. Our work suggests ingredients for designing emergent magnetic topological phenomena by pyrochlore heterostructures.