Authors
Mariangela Rondanelli, Antonella Riva, Pietro Allegrini, Milena Anna Faliva, Maurizio Naso, Gabriella Peroni, Mara Nichetti, Clara Gasparri, Daniele Spadaccini, Giancarlo Iannello, Vittoria Infantino, Teresa Fazia, Luisa Bernardinelli, Simone Perna
Publication date
2020/4/21
Journal
Journal of pain research
Pages
761-770
Publisher
Taylor & Francis
Description
Purpose
To evaluate the efficacy of a new food-grade lecithin formulation of standardized extracts of Zingiber officinale and Acmella oleracea on pain and inflammation.
Patients and Methods
Pilot study with one-group pretest–posttest quasi-experimental design in which 50 subjects with moderate knee osteoarthritis (OA) (mean age: 62.46±8.45) were supplied for four weeks with two tablets/day.
Results
Primary outcomes were 1) the evaluation of pain intensity, by a 30-day visual analogue scale (VAS) and 2) the assessment of knee function by WOMAC (Western Ontario and McMaster Universities Arthritis) Index and by Tegner Lysholm Knee Scoring collected at baseline, at 15 and 30 days after treatment. Secondary outcomes were 3) health-related quality of life, by the ShortForm36 (SF-36); 4) inflammation grade by C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR); and 5) body composition by dual …
Scholar articles
M Rondanelli, A Riva, P Allegrini, MA Faliva, M Naso… - Journal of pain research, 2020