Authors
Ulrich Desselberger, Miren Iturriza‐Gómara, Jim J Gray
Publication date
2001/5/16
Source
Gastroenteritis Viruses: Novartis Foundation Symposium 238
Volume
238
Pages
125-152
Publisher
John Wiley & Sons, Ltd
Description
There is extensive antigenic and genomic diversity among co‐circulating human rotaviruses. They are differentiated into groups, subgroups and types. There are at least 7 groups (A–G) and 4 subgroups within group A. To distinguish types within group A, a dual classification system has been established with the glycoprotein VP7 defining G types, and the protease‐sensitive protein VP4 defining P types. At least 14 G types and more than 20 P types have been distinguished, of which at least 10 G types and at least 11 P types have been found in humans. Using the typing system, the complex molecular epidemiology of rotaviruses was investigated. Rotaviruses of different G and P types co‐circulate. The main types found are G1P1A[8], G2P1B[4], G3P1A[8], G4P1A[8]; their relative incidence rates change over time in any one location and are different at the same time between different locations. Viruses with G/P …
Total citations
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Scholar articles
U Desselberger, M Iturriza‐Gómara, JJ Gray - Gastroenteritis Viruses: Novartis Foundation …, 2001