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We explore the mid-infrared (mid-IR) through ultraviolet (UV) spectral energy distributions (SEDs) of 119,652 luminous broad-lined quasars with 0.064< z< 5.46 using mid-IR data from Spitzer and WISE, near-infrared data from the Two Micron All Sky Survey and UKIDSS, optical data from the Sloan Digital Sky Survey, and UV data from the Galaxy Evolution Explorer. The mean SED requires a bolometric correction (relative to 2500 Å) of BC 2500 Å= 2.75±0.40 using the integrated light from 1 μm–2 keV, and we further explore the range of bolometric corrections exhibited by individual objects. In addition, we investigate the dependence of the mean SED on various parameters, particularly the UV luminosity for quasars with 0.5≲ z≲ 3 and the properties of the UV emission lines for quasars with z≳ 1.6; the latter is a possible indicator of the strength of the accretion disk wind, which is expected to be SED-dependent …