Authors
Lukas Dominique Josef Fiederer, Johannes Vorwerk, Felix Lucka, Moritz Dannhauer, Shan Yang, Matthias Dümpelmann, Andreas Schulze-Bonhage, Ad Aertsen, Oliver Speck, Carsten H Wolters, Tonio Ball
Publication date
2016/3/1
Journal
NeuroImage
Volume
128
Pages
193-208
Publisher
Academic Press
Description
Reconstruction of the electrical sources of human EEG activity at high spatio-temporal accuracy is an important aim in neuroscience and neurological diagnostics. Over the last decades, numerous studies have demonstrated that realistic modeling of head anatomy improves the accuracy of source reconstruction of EEG signals. For example, including a cerebro-spinal fluid compartment and the anisotropy of white matter electrical conductivity were both shown to significantly reduce modeling errors. Here, we for the first time quantify the role of detailed reconstructions of the cerebral blood vessels in volume conductor head modeling for EEG. To study the role of the highly arborized cerebral blood vessels, we created a submillimeter head model based on ultra-high-field-strength (7 T) structural MRI datasets. Blood vessels (arteries and emissary/intraosseous veins) were segmented using Frangi multi-scale vesselness …
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