View article

Objectives: Nanomaterial production and the number of people directly in contact with these materials are increasing. Yet, little is known on the association between exposure and corresponding risks, such as pulmonary inflammation and oxidative stress.

Methods: Condensation Particle Counters, a DustTrak™ and Scanning Mobility Particle Sizer™ quantified real-time size, mass and number concentrations in a nanostructure particle pilot-scale production facility, using a high-temperature gas-phase process, over a 25-day period. Temporal and spatial analysis of particle concentrations and sizes was performed during production, maintenance and handling. Number-based particle retention of breathing mask filters used under real-time production and exposure conditions in the workplace was quantified.

Results: The results demonstrate elevated number concentrations during production, which can …