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Interoperability is a fundamental problem in distributed systems, and an increasingly difficult problem given the level of heterogeneity and dynamism exhibited by contemporary systems. While progress has been made, we argue that complexity is now at a level such that existing approaches are inadequate and that a major re-think is required to identify principles and associated techniques to achieve this central property of distributed systems. In this paper, we postulate that emergent middleware is the right way forward; emergent middleware is a dynamically generated distributed system infrastructure for the current operating environment and context. In particular, we focus on the key role of ontologies in supporting this process and in providing underlying meaning and associated reasoning capabilities to allow the right run-time choices to be made. The paper presents the Connect middleware architecture …