Authors
Carolyn SP Lam, Anna Giczewska, Karen Sliwa, Frank Edelmann, Jens Refsgaard, Edimar Bocchi, Justin A Ezekowitz, Adrian F Hernandez, Christopher M O’Connor, Lothar Roessig, Mahesh J Patel, Burkert Pieske, Kevin J Anstrom, Paul W Armstrong, Eduardo Roque Perna, Maria Galarza Salazan, Ignacio MacKinnon, Florencia Eden, Luis Cartasegna, Viviana Novas, Hugo A Luquez, Ana Cenci, Miguel Angel Hominal, Maria Veronica Bianchini, Rodolfo Andres Ahuad Guerrero, Andrea Alvarez D'Amelio, Carlos Alberto Poy, Maria Poy, Claudio R Majul, Cecilia Currao, Ezequiel Hector Vottero, Mariana Perrin, Cesar Javier Zaidman, Vanesa Espinosa, Gerardo Zapata, Luciana Arias, Sonia Angelica Sassone, Lucas Tonelli, Daniel Agustin Chirino Navarta, Maria Mangini, Jesus Cuadrado, Paula Bordoni, David Kaye, Kaye Carter, John Amerena, Toni Shanahan, Scott McKenzie, Kathryn Stibijl, Carmine De Pasquale, Fiona Wollaston, David Martin Colquhoun, Antonio Ferreira-Jardim, Alicia Chan, Greer Dymmott, Brendan McQuillan, Katayun Mohammadi, David Cross, Judy Jeffrey, Andrew Sindone, Magdalena Gebran, Amit Shah, Gill Tulloch, Maged William, Bets Conway, James Wong, Donna North, Dirk von Lewinski, Karin Brandner, Uta Hoppe, Kristen Kopp, Regina Steringer Mascherbauer, Claudia Steinkellner, Diana Bonderman, Christina Binder, Christopher Adlbrecht, Maria Leitgeb, Anne-Catherine Pouleur, Florence Sinnaeve, Matthias Dupont, Carola Claes, Michel De Ceuninck, Els Vancayseele, Philippe Timmermans, Gregory Van Genechten, Pierre Troisfontaines, Mireille Massoz, Thao Thanh Huynh, Caroline Boudreault, Eric Sabbah, Isabelle Chausse, Ronald Leonard Bourgeois, Karen Boyd, Michael Heffernan, Marie Birch, Marie-Claude Parent, Helene Brown, A Shekhar Pandey, Tatiana Ballivian, Nadia Giannetti, Reza Sahebjamei, Saul Vizel, Beverley Fox, Dennis Wayne Rupka, Sandi Thiessen, Christian Constance, Marie-France Gauthier, Justin Ezekowitz, Quentin Kushnerik, Allan Schaffer, Wendy Janz, Michael Chan, Jennifer Knight, Serge Lepage, Daniel Soucy, John D Parker, Elaine Hsu, Lisa Mielniczuk, Ermina Moga, Benoit Coutu, Julie Fleury, Paul MacDonald, Kathleen Hines, Diego Delgado, Natalia Nugaeva, Ying Sia, Isabelle Roy, David Laflamme, Christel Simard, Gilbert Gosselin, Katia Drouin, Brian Clarke, Kimberley Ronak, Denis Saulnier, Melissa Cote, Bruce Alexander Sussex, Bernadette Druken, Miroslaw Rajda, Jayne Falkenham, Ashok Mukherjee, Beverly Bozek, Gordon Willy Pak Ling Moe, Carlos Fernando, Sebastien Bergeron, Hugo Tremblay, Marcelo Coelho Shibata, Bonnie Woloschuk, Dante Manyari, Tracy Cleveland, Frank Nigro, Crystal Forsyth
Publication date
2021/6/1
Journal
JAMA cardiology
Volume
6
Issue
6
Pages
706-712
Publisher
American Medical Association
Description
Importance
The period following heart failure hospitalization (HFH) is a vulnerable time with high rates of death or recurrent HFH.
Objective
To evaluate clinical characteristics, outcomes, and treatment response to vericiguat according to prespecified index event subgroups and time from index HFH in the Vericiguat Global Study in Subjects With Heart Failure With Reduced Ejection Fraction (VICTORIA) trial.
Design, Setting, and Participants
Analysis of an international, randomized, placebo-controlled trial. All VICTORIA patients had recent (<6 months) worsening HF (ejection fraction <45%). Index event subgroups were less than 3 months after HFH (n = 3378), 3 to 6 months after HFH (n = 871), and those requiring outpatient intravenous diuretic therapy only for worsening HF (without HFH) in the previous 3 months (n = 801). Data were analyzed between May 2, 2020, and May 9, 2020.
Intervention
Vericiguat …
Scholar articles
CSP Lam, A Giczewska, K Sliwa, F Edelmann… - JAMA cardiology, 2021