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The development of divergence-time estimation methods has been an active area of research since the early 1960s, when the molecular clock was first postulated by Zuckerkandl and Pauling. Thanks to technological and computational improvements, more powerful and cutting-edge techniques and algorithms have been developed to better understand species evolution at the molecular level. These have led to improved methods for molecular clock dating of speciation events. During the past two decades, the approaches for DNA sequencing have substantially advanced and their costs have decreased, thus enabling large-scale genome-sequencing projects that aim to sequence all species in the tree of life. Being able to access thousands of complete genomes, however, has brought new biological and computational challenges to phylogenomic analyses. We might have more data, but also new …