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This chapter provides a discussion of the important research topics for understanding behavioral responses to highly automated vehicles (AVs) as discussed at a breakout session at the Automated Vehicle Symposium (AVS) 2018. The session, and thus this chapter, highlights the need for valid behavioral data on which to base assumptions, models, forecasts, and impacts to inform AV adoption behaviors, the pathways of AV ownership and use, and the potential impact of AVs on human activity-travel behaviors and longer-term location choices.