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This study operationalizes the knowledge-based dynamic capabilities (KBDC) that act as drivers of innovation performance in innovation ecosystems, across different market economies. Innovation ecosystems facilitate the flow of resources to transform ideas into reality. In turn, KBDC provide a means to create and share expertise, which contributes to the diversification of the economy, and allow businesses to reach beyond their own boundaries to create value for customers in new ways. Employing partial least squares path analysis, four constructs, namely knowledge creation, knowledge diffusion, knowledge absorption and knowledge impact, are comparatively analyzed. Across all four constructs, knowledge creation is the biggest driver of innovation performance, and the strongest predictor of innovation performance in developed and developing market economies. Knowledge absorption is the strongest …