Authors
Pediatric Eye Disease Investigator Group
Publication date
2008/8/11
Journal
Archives of ophthalmology
Volume
126
Issue
8
Pages
1039-1044
Publisher
American Medical Association
Description
Objective
To determine the visual acuity outcome at age 10 years for children younger than 7 years when enrolled in a treatment trial for moderate amblyopia.
Methods
In a multicenter clinical trial, 419 children with amblyopia (visual acuity, 20/40-20/100) were randomized to patching or atropine eyedrops for 6 months. Two years after enrollment, a subgroup of 188 children entered long-term follow-up. Treatment after 6 months was at the discretion of the investigator; 89% of children were treated.
Main Outcome Measure
Visual acuity at age 10 years with the electronic Early Treatment Diabetic Retinopathy Study test.
Application to Clinical Practice
Patching and atropine eyedrops produce comparable improvement in visual acuity that is maintained through age 10 years.
Results
The mean amblyopic eye acuity, measured in 169 patients, at age 10 years was 0.17 logMAR (logarithm of the minimum angle of resolution …
Total citations
20092010201120122013201420152016201720182019202020212022202320249916102010212051623211517307