Authors
Roberto Hornero, Daniel Abásolo, Javier Escudero, Carlos Gómez
Publication date
2009/1/28
Journal
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Volume
367
Issue
1887
Pages
317-336
Publisher
The Royal Society
Description
The aim of the present study is to show the usefulness of nonlinear methods to analyse the electroencephalogram (EEG) and magnetoencephalogram (MEG) in patients with Alzheimer's disease (AD). The following nonlinear methods have been applied to study the EEG and MEG background activity in AD patients and control subjects: approximate entropy, sample entropy, multiscale entropy, auto-mutual information and Lempel–Ziv complexity. We discuss why these nonlinear methods are appropriate to analyse the EEG and MEG. Furthermore, the performance of all these methods has been compared when applied to the same databases of EEG and MEG recordings. Our results show that EEG and MEG background activities in AD patients are less complex and more regular than in healthy control subjects. In line with previous studies, our work suggests that nonlinear analysis techniques could be useful in AD …
Total citations
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Scholar articles
R Hornero, D Abásolo, J Escudero, C Gómez - Philosophical Transactions of the Royal Society A …, 2009