View article

Methods| This cohort study (September 1, 2021-January 31, 2022) was approved by the MetroHealth System institutional review board (IRB); the need for informed consent was waived owing to use of deidentified patient data. We used the Tri-NetX Analytics Platform to access aggregated and deidentified electronic health records of 90 million patients from 66 health care organizations.

TriNetX built-in analytic functions permit patientlevel analyses while only reporting population-level data. Patients represented 28% of the US population from 50 states covering diverse geographic, age, race, income, and insurance groups. 3 Self-identified race and ethnicity were included owing to their association with SARS-CoV-2 infection risk and outcomes.