Authors
Bernadette J Stolz, Tegan Emerson, Satu Nahkuri, Mason A Porter, Heather A Harrington
Publication date
2021/5/19
Journal
Journal of Physics: Complexity
Volume
2
Issue
3
Pages
035006
Publisher
IOP Publishing
Description
We use methods from computational algebraic topology to study functional brain networks in which nodes represent brain regions and weighted edges encode the similarity of functional magnetic resonance imaging (fMRI) time series from each region. With these tools, which allow one to characterize topological invariants such as loops in high-dimensional data, we are able to gain understanding of low-dimensional structures in networks in a way that complements traditional approaches that are based on pairwise interactions. In the present paper, we use persistent homology to analyze networks that we construct from task-based fMRI data from schizophrenia patients, healthy controls, and healthy siblings of schizophrenia patients. We thereby explore the persistence of topological structures such as loops at different scales in these networks. We use persistence landscapes and persistence images to represent …
Total citations
20202021202220232024277194
Scholar articles
BJ Stolz, T Emerson, S Nahkuri, MA Porter… - Journal of Physics: Complexity, 2021