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This exploratory, qualitative study examined the risk and protective factors of Micronesian middle and high school students in Hawai’i. Forty one Micronesian youth participated in 9 focus groups that explored their experiences within their schools, families, and communities. The findings describe youths’ experiences of ecological stress beginning with their migration to Hawai’i, and the potential outcomes of this stress (eg, fighting, gangs, and drug use). Cultural buffers, such as traditional practices and culturally specific prevention programs, were described as aspects that prevented adverse outcomes. Implications for prevention practice are discussed.