Authors
Claribel P Simmons, Filippos Koinis, Marie T Fallon, Kenneth C Fearon, Jo Bowden, Tora S Solheim, Bjorn Henning Gronberg, Donald C McMillan, Ioannis Gioulbasanis, Barry J Laird
Publication date
2015/6/1
Journal
Lung Cancer
Volume
88
Issue
3
Pages
304-309
Publisher
Elsevier
Description
Objectives
In patients with advanced incurable lung cancer deciding as to the most appropriate treatment (e.g. chemotherapy or supportive care only) is challenging. In such patients the TNM classification system has reached its ceiling therefore other factors are used to assess prognosis and as such, guide treatment. Performance status (PS), weight loss and inflammatory biomarkers (Glasgow Prognostic Score (mGPS)) predict survival in advanced lung cancer however these have not been compared. This study compares key prognostic factors in advanced lung cancer.
Materials and methods
Patients with newly diagnosed advanced lung cancer were recruited and demographics, weight loss, other prognostic factors (mGPS, PS) were collected. Kaplan–Meier and Cox regression methods were used to compare these prognostic factors.
Results
390 patients with advanced incurable lung cancer were recruited; 341 …
Scholar articles
CP Simmons, F Koinis, MT Fallon, KC Fearon… - Lung Cancer, 2015