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The LRFD method employs the geotechnical resistance factor (GRF) to design pile foundations. Different resistance mechanisms at the end and side of the pile lead to the requirement of separate GRF values for the shaft and toe capacities. The main aim of this study is to establish regionally separate GRFs for the toe and shaft resistances of pile foundations using different reliability analysis methods. A comprehensive database was gathered from field tests conducted in Alberta, Canada, involved 623 Pile Driving Analyzer (PDA) tests and 28 static load tests. Two criteria called ‘70% rule’ and ‘R ratio’ were used to evaluate the results. Due to certain limitations in the definition of the ‘70% rule’, the ‘R ratio’ method yielded more realistic results. The results indicated that employing separate GRFs for shaft and toe resistances can lead to a significant increase in the factored pile resistance when compared to the values …