Authors
Sungano Mharakurwa, Zvifadzo Matsena-Zingoni, Nobert Mudare, Charmaine Matimba, Tanatswa Xuxa Gara, Aramu Makuwaza, Gladys Maponga, Shungu Munyati, Lovemore Gwanzura, Susan L Mutambu, Peter Mason, Tamaki Kobayashi, Nicholas Midzi, William J Moss, Matthew M Ippolito
Publication date
2021/1/15
Journal
The Journal of infectious diseases
Volume
223
Issue
2
Pages
306-309
Publisher
Oxford University Press
Description
Removal of chloroquine from national malaria formularies can lead to the reversion of resistant Plasmodium falciparum to wild-type. We report a steep decline in chloroquine-resistant P falciparum within 10 years of national discontinuation of chloroquine monotherapy in Zimbabwe. Drug resistance surveillance is a vital component of malaria control programs, and the experience with chloroquine in Zimbabwe and elsewhere in sub-Saharan Africa is illustrative of the potentially rapid and dramatic impact of drug policy on antimalarial resistance.
Scholar articles
S Mharakurwa, Z Matsena-Zingoni, N Mudare… - The Journal of infectious diseases, 2021