Authors
Christian Pagnoux, Raphaèle Seror, Corneliu Henegar, Alfred Mahr, Pascal Cohen, Véronique Le Guern, Boris Bienvenu, Luc Mouthon, Loïc Guillevin
Publication date
2010/2
Journal
Arthritis & Rheumatism: Official Journal of the American College of Rheumatology
Volume
62
Issue
2
Pages
616-626
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Description
Objective
Previous studies of polyarteritis nodosa (PAN) included patients with microscopic polyangiitis, because these entities were not distinguished prior to the Chapel Hill Consensus Conference (CHCC). This study was undertaken to describe the main characteristics of and long‐term outcomes in patients with well‐characterized PAN diagnoses.
Methods
We conducted a systematic retrospective study of 348 patients who were diagnosed as having PAN between March 1963 and October 2005, were registered in the French Vasculitis Study Group database, and satisfied the American College of Rheumatology and CHCC criteria. Patient characteristics and outcomes were analyzed and compared according to hepatitis B virus (HBV) status.
Results
At diagnosis, the mean ± SD age was 51.2 ± 17.3 years. The most frequent findings were general symptoms (93.1%), neurologic manifestations (79%), skin …
Total citations
20102011201220132014201520162017201820192020202120222023202462528394134364835565458474221