Authors
Corneliu Henegar, Christian Pagnoux, Xavier Puéchal, Jean‐Daniel Zucker, Avner Bar‐Hen, Véronique Le Guern, Mona Saba, Denis Bagnères, Olivier Meyer, Loïc Guillevin, French Vasculitis Study Group
Publication date
2008/5
Journal
Arthritis & Rheumatism
Volume
58
Issue
5
Pages
1528-1538
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Description
Objective
To establish a set of clinical and paraclinical criteria potentially useful as a diagnostic screening tool for polyarteritis nodosa (PAN).
Methods
The abilities of individual descriptive items to predict a diagnosis of PAN were evaluated by screening available data from 949 patients from the French Vasculitis Study Group database, including 262 with PAN and 687 with control vasculitides. Selected items were tested in a logistic regression model to establish a minimal set of nonredundant PAN‐predictive criteria. The discriminative accuracy of these items and of the American College of Rheumatology (ACR) 1990 criteria were assessed by reapplying them to the initial patient sample and a subgroup restricted to PAN and microscopic polyangiitis (MPA) patients. A computer simulation procedure was conducted on artificially generated patient data to evaluate the usefulness of these criteria in predicting a …
Total citations
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