Authors
Catherine GY Ngan, Cathal D O’Connell, Romane Blanchard, Mitchell Boyd-Moss, Richard J Williams, J Bourke, A Quigley, P McKelvie, Robert MI Kapsa, PFM Choong
Publication date
2019/3/26
Journal
Biomedical Materials
Volume
14
Issue
3
Pages
035007
Publisher
IOP Publishing
Description
3D printing is a rapid and accessible fabrication technology that engenders creative custom design solutions for cell scaffolds, perfusion systems and cell culture systems for tissue engineering. Critical to its success is the biocompatibility of the materials used, which should allow long-term tissue culture without affecting cell viability or inducing an inflammatory response for in vitro and in vivo applications. Polyjet 3D printers offer arguably the highest resolution with the fewest design constraints of any commercially available 3D printing systems. Although widely used for rapid-prototyping of medical devices and 3D anatomical modelling, polyjet printing has not been adopted by the tissue engineering field, largely due to the cytotoxicity of leachates from the printed parts. Biocompatibility in the context of cell culture is not commonly addressed for polyjet materials, as they tend to be optimised for their ability to fabricate …
Total citations
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