Authors
Rathan M Subramaniam, Catalina Suarez-Cuervo, Renee F Wilson, Sharon Turban, Allen Zhang, Cheryl Sherrod, Jonathan Aboagye, John Eng, Michael J Choi, Susan Hutfless, Eric B Bass
Publication date
2016/3/15
Source
Annals of internal medicine
Volume
164
Issue
6
Pages
406-416
Publisher
American College of Physicians
Description
Background
N-acetylcysteine, sodium bicarbonate, statins, and ascorbic acid have been studied for reducing contrast-induced nephropathy (CIN).
Purpose
To evaluate the comparative effectiveness of interventions to reduce CIN in adults receiving contrast media.
Data Sources
MEDLINE, EMBASE, Cochrane Library, ClinicalTrials.gov, and Scopus databases through June 2015. Risk of bias and overall strength of evidence (SOE) of studies were assessed.
Study Selection
Randomized, controlled trials of N-acetylcysteine, sodium bicarbonate, statins, or ascorbic acid that used intravenous (IV) or intra-arterial contrast media and defined CIN with enough data for meta-analysis.
Data Extraction
Two reviewers independently extracted data and assessed …
Total citations
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