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Glioma is the most common histological type of primary central nervous system cancer, accounting for 81% of all malignant brain tumors (1). Astrocytomas, oligodendrogliomas, oligoastrocytomas, and ependymomas are all types of gliomas. The World Health Organization (WHO) defines gliomas into four categories; the first two grades and the last two grades are further classified as low-grade glioma (LGG) and high-grade glioma (HGG). The poor 5-year overall survival (OS) rate for WHO grade IV glioma patients are 6.8%(2, 3). Glioblastoma (GBM) is the most aggressive kind of grade IV astrocytoma, accounting for 45% of gliomas and the 5-year OS rate of GBM patients is 5%. Treatment for gliomas generally comprises surgical excision, radiation, and temozolomide chemotherapy. Previous randomized clinical studies indicated that the addition of tumor-treating fields to routine treatment increased life expectancy by 4 months (4, 5).