Authors
Christopher S Hollenbeak, Fenghai Duan, Rathan M Subramaniam, Alexander Taurone, JoRean Sicks, Val J Lowe, Brendan C Stack Jr
Publication date
2024/2/14
Journal
Head & Neck
Publisher
John Wiley & Sons, Inc.
Description
Background
This study examined the trajectory of health‐related quality of life (HRQoL) for patients with clinical stage N0 HNSCC enrolled in ACRIN 6685 who underwent elective neck dissection(s).
Methods
HRQoL of 230 patients in the ACRIN 6685 trial was measured prospectively up to 2 years following surgery using the University of Washington Quality of Life instrument.
Results
General Health Within the Last 7 Days did not differ significantly from baseline at any follow‐up. General Health Relative to Before Cancer fell significantly by 5.8 points following surgery (p = 0.048), and then returned to 3.0 points above baseline at 1 year (p = 0.65). For Overall Quality of Life, HRQoL fell significantly by 4.3 points following surgery (p = 0.031) and then returned to levels not significantly different from baseline.
Conclusions
Patients with stage N0 HNSCC experience significant declines in HRQoL …
Scholar articles
CS Hollenbeak, F Duan, RM Subramaniam, A Taurone… - Head & Neck, 2024