Authors
Yasuo Kato, Hiroyuki Yoshida, Kazuaki Shoji, Yukio Sato, Noriyuki Nakajima, Shinjiro Ogita
Publication date
2009/8/19
Journal
Tetrahedron Letters
Volume
50
Issue
33
Pages
4751-4753
Publisher
Pergamon
Description
We developed a facile method of enzyme-mediated conversion of 6-tuliposide to α-methylene-γ-butyrolactone (tulipalin). We used a tuliposide-converting enzyme for the conversion of 6-tuliposides extracted from tulip tissues into the corresponding tulipalins in high yields within 2h at pH 7.0. The resulting tulipalins were selectively extracted by using several organic solvents.
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