Authors
Alina V Brenner, Mykola D Tronko, Maureen Hatch, Tetyana I Bogdanova, Valery A Oliynik, Jay H Lubin, Lydia B Zablotska, Valery P Tereschenko, Robert J McConnell, Galina A Zamotaeva, Patrick O’Kane, Andre C Bouville, Ludmila V Chaykovskaya, Ellen Greenebaum, Ihor P Paster, Victor M Shpak, Elaine Ron
Publication date
2011/7/1
Journal
Environmental health perspectives
Volume
119
Issue
7
Pages
933-939
Publisher
National Institute of Environmental Health Sciences
Description
Background: Current knowledge about Chornobyl-related thyroid cancer risks comes from ecological studies based on grouped doses, case–control studies, and studies of prevalent cancers.
Objective: To address this limitation, we evaluated the dose–response relationship for incident thyroid cancers using measurement-based individual iodine-131 (I-131) thyroid dose estimates in a prospective analytic cohort study.
Methods: The cohort consists of individuals < 18 years of age on 26 April 1986 who resided in three contaminated oblasts (states) of Ukraine and underwent up to four thyroid screening examinations between 1998 and 2007 (n = 12,514). Thyroid doses of I-131 were estimated based on individual radioactivity measurements taken within 2 months after the accident, environmental transport models, and interview data. Excess radiation risks were estimated using Poisson regression models.
Results: Sixty …
Total citations
Scholar articles
AV Brenner, MD Tronko, M Hatch, TI Bogdanova… - Environmental health perspectives, 2011