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Objective: To compare the effectiveness of tepid sponging and antipyretic drug versus only antipyretic drug among febrile children. Design: Randomized controlled trial. Setting: Tertiary care hospital. Participants: 150 children 6 mo--12 yr age with axillary temperature≥ 101 F. Intervention: Tepid sponging and antipyretic drug (Paracetamol)(n= 73) or only antipyretic drug (Paracetamol)(n= 77). Main outcome measures: Reduction of body temperature and level of comfort. Results: The reduction of body temperature in the tepid sponging and antipyretic drug group was significantly faster than only antipyretic group; however, by the end of 2 hours both groups had reached the same degree of temperature. The children in tepid sponging and antipyretic drug had significantly higher discomfort than only antipyretic group, but the discomfort was mostly mild. Conclusion: Apart from the initial rapid temperature reduction …