Authors
Khalid Khan, Ahmed A Ismail, Gaafar Abdel Rasoul, Matthew R Bonner, Michael R Lasarev, Olfat Hendy, Manal Al-Batanony, Alice L Crane, Steven T Singleton, James R Olson, Diane S Rohlman
Publication date
2014/3/1
Journal
BMJ open
Volume
4
Issue
3
Pages
e004177
Publisher
British Medical Journal Publishing Group
Description
Objectives
Occupational exposure of organophosphorus pesticides, such as chlorpyrifos (CPF), in adolescents is of particular concern because of the potential vulnerability of the developing neurological system. The objectives of this study were to examine how neurological symptoms reported over the application season vary across time, whether these effects are reversible postapplication and if there are associations between CPF biomarkers and neurological symptoms in an adolescent study population.
Setting
The longitudinal study was conducted in two agricultural districts of Menoufia Governorate, Egypt between April 2010 and January 2011.
Participants
Male adolescent participants, including CPF applicators (n=57) and non-applicators (n=38), were recruited.
Primary and secondary outcome measures
Self-reported data for 25 neurological symptoms were collected at 32 time points over the 8-month …
Scholar articles
K Khan, AA Ismail, GA Rasoul, MR Bonner… - BMJ open, 2014