Authors
Naheed Mahmood, Cosimo Pizza, Rita Aquino, Nunziatina De Tommasi, Sonia Piacente, Susan Colman, Andrew Burke, Alan J Hay
Publication date
1993/10/1
Journal
Antiviral research
Volume
22
Issue
2-3
Pages
189-199
Publisher
Elsevier
Description
Of a variety of flavanoids, the flavans were generally more effective than flavones and flavanones in selective inhibition of HIV-1, HIV-2 or SIV infection. Studies of their effects on the binding of sCD4 and antibody to gp120 indicated that the effective compounds interact irreversibly with gp120 to inactivate virus infectivity and block infection.
Total citations
Scholar articles
N Mahmood, C Pizza, R Aquino, N De Tommasi… - Antiviral research, 1993