Authors
Rosdali Diaz-Coronado, Eddy Hernandez-Broncano, Tatiana Negreiros-Chinchihuara, Sandro Casavilca-Zambrano, Danny A Campos, Ronny E Baticulon, Ana Patricia A Alcasabas, Kathleen Khu, Ahmer Hamid, Nida Zia, Yumna Syed, Bisma Yousuf, Nuha Omran, Hend A Sharafeldin, Khaled Seddik, Shady Fadel, Estuardo Pineda, Ana Polanco, Jen Chun Foo, Revathi Rajagopal, Dharmendra Ganesan, Regina Navarro-Martin del Campo, Luis Arredondo-Navarro, Gabriela Escamilla, Rafael Ruvalcaba, Beatriz García, Paloma Amarillo, Cesar A Villegas, Godwin Job, Lane Faughnan, Meenakshi Devidas, Ibrahim Qaddoumi, Daniel C Moreira
Publication date
2024/6
Journal
Neuro-Oncology
Volume
26
Issue
Suppl 4
Pages
0
Publisher
Oxford University Press
Description
METHODS
Patients< 18 years old with newly diagnosed MB, treated from January 2014 to December 2018 in Egypt, El Salvador, Malaysia, Mexico, Pakistan, Peru, Philippines, and Uruguay were included. Data on demographics, clinical presentation, treatment and biological characteristics were collected. Factors associated with patient outcomes were analyzed.
RESULTS
The study included 330 patients with a median age of 7.7 years. Of these, 49 patients (15%) were< 3 years old and 212 (64%) were male. Eighty-eight patients (26%) had experienced symptoms for> 3 months at diagnosis. Gross total resection was achieved in 153 (47%) patients. Sixty-three patients (19%) experienced post-operative infections. Eighty-four patients (24%) had metastatic disease at diagnosis. The histologic subtype was not specified in 98 cases (30%), and 25 patients (7%) had molecular subgroups identified. Radiotherapy was …
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R Diaz-Coronado, E Hernandez-Broncano… - Neuro-Oncology, 2024