Authors
Ahmet A Yanik, Min Huang, Alp Artar, Tsung-Yao Chang, Hatice Altug
Publication date
2010/11/7
Conference
2010 23rd Annual Meeting of the IEEE Photonics Society
Pages
162-163
Publisher
IEEE
Description
We introduce a novel hybrid platform merging label free nanoplasmonic biosensing with actively controlled nanofluidic analyte delivery to overcome mass transport limitations. We show 14-fold improvement in mass transport rate constants appearing in the exponentials. Performances of the surface biosensors are often controlled by the analyte delivery rate to the sensing surface instead of the sensors intrinsic detection capabilities. In a microfluidic channel, diffusive analyte transport to the biosensor surface severely limits the analyte delivery as a result the biosensors performance. At low concentrations, this limitation, which is commonly known as mass transport problem, causes impractically long detection times extending from days to months for nano-sensors. Although an extensive work has been done on the subject, previous approaches based on stirring and various mixing strategies seem to result in moderate …
Total citations
20172018201911
Scholar articles
AA Yanik, M Huang, A Artar, TY Chang, H Altug - 2010 23rd Annual Meeting of the IEEE Photonics …, 2010