Authors
Steven P Engebretson, Leslie G Hyman, Bryan S Michalowicz, Elinor R Schoenfeld, Marie C Gelato, Wei Hou, Elizabeth R Seaquist, Michael S Reddy, Cora E Lewis, Thomas W Oates, Devjit Tripathy, James A Katancik, Philip R Orlander, David W Paquette, Naomi Q Hanson, Michael Y Tsai
Publication date
2013/12/18
Journal
Jama
Volume
310
Issue
23
Pages
2523-2532
Publisher
American Medical Association
Description
Importance
Chronic periodontitis, a destructive inflammatory disorder of the supporting structures of the teeth, is prevalent in patients with diabetes. Limited evidence suggests that periodontal therapy may improve glycemic control.
Objective
To determine if nonsurgical periodontal treatment reduces levels of glycated hemoglobin (HbA1c) in persons with type 2 diabetes and moderate to advanced chronic periodontitis.
Design, Setting, and Participants
The Diabetes and Periodontal Therapy Trial (DPTT), a 6-month, single-masked, multicenter, randomized clinical trial. Participants had type 2 diabetes, were taking stable doses of medications, had HbA1c levels between 7% and less than 9%, and untreated chronic periodontitis. Five hundred fourteen participants were enrolled between November 2009 and March 2012 from diabetes and dental clinics and communities affiliated with 5 academic medical centers …
Total citations
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