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The qualitative assessment of groundwater and health risk is an integral step in sustainable development of the region. The present study mainly focuses on the assessment of human health risk in the Shahada tehsil of Nandurbar District, North Maharashtra, India due to the nitrate and fluoride contamination in subsurface water resources due to the anthropogenic inputs. In view of this, forty-five (45) representative water samples were collected in month of March 2019 and were assessed for major physiochemical parameters using guidelines of APHA standard procedures. The analytical results were compared with the drinking standards of World Health Organization (WHO) and Bureau of Indian (BIS). The analytical results depict that EC, TDS, TH, Ca²⁺, Mg²⁺, HCO₃⁻, Cl⁻, NO₃⁻ and F⁻ surpassed the desirable limit (DL) and permissible limit (PL). The statistical analysis includes Correlation Analysis (CA) and …