Authors
Manuel K Rausch, Alexander M Zöllner, Martin Genet, Brian Baillargeon, Wolfgang Bothe, Ellen Kuhl
Publication date
2017/2
Journal
International journal for numerical methods in biomedical engineering
Volume
33
Issue
2
Pages
e02788
Description
Functional mitral regurgitation, a backward leakage of the mitral valve, is a result of left ventricular growth and mitral annular dilatation. Its gold standard treatment is mitral annuloplasty, the surgical reduction in mitral annular area through the implantation of annuloplasty rings. Recurrent regurgitation rates may, however, be as high as 30% and more. While the degree of annular downsizing has been linked to improved long‐term outcomes, too aggressive downsizing increases the risk of ring dehiscences and significantly impairs repair durability. Here, we prototype a virtual sizing tool to quantify changes in annular dimensions, surgically induced tissue strains, mitral annular stretches, and suture forces in response to mitral annuloplasty. We create a computational model of dilated cardiomyopathy onto which we virtually implant annuloplasty rings of different sizes. Our simulations confirm the common intuition that …
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Scholar articles
MK Rausch, AM Zöllner, M Genet, B Baillargeon… - International journal for numerical methods in …, 2017