Authors
Manuel Houmard, Qiang Fu, Martin Genet, Eduardo Saiz, Antoni P Tomsia
Publication date
2013/10/1
Journal
Journal of Biomedical Materials Research Part B: Applied Biomaterials
Volume
101
Issue
7
Pages
1233-1242
Description
Hydroxyapatite/β‐tricalcium phosphate (HA/β‐TCP) composite scaffolds have shown great potential for bone‐tissue engineering applications. In this work, ceramic scaffold with different HA/β‐TCP compositions (pure HA, 60HA/40β‐TCP, and 20HA/80β‐TCP) were fabricated by a robotic‐assisted deposition (robocasting) technique using water‐based hydrogel inks. A systematic study was conducted to investigate the porosity, mechanical property, and degradation of the scaffolds. Our results indicate that, at a similar volume porosity, the mechanical strength of the sintered scaffolds increased with the decreasing rod diameter. The compressive strength of the fabricated scaffolds (porosity ≈ 25–80 vol %) varied between ∼3 and ∼50 MPa, a value equal or higher than that of human cancellous bone (2–12 MPa). Although there was a slight increase of Ca and P ions in water after 5 month, no noticeable degradation of …
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Scholar articles
M Houmard, Q Fu, M Genet, E Saiz, AP Tomsia - Journal of Biomedical Materials Research Part B …, 2013