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Sedimentological data and hydrogen isotopic measurements of leaf wax long-chain n-alkanes (δD wax) from an alpine lake sediment archive on the southeastern Tibetan Plateau (Paru Co) provide a Holocene perspective of Indian summer monsoon (ISM) activity. The sedimentological data reflect variations in lake level and erosion related to local ISM rainfall over the Paru Co catchment, whereas δD wax reflects integrated, synoptic-scale ISM dynamics. Our results indicate that maximum ISM rainfall occurred between 10.1 and∼ 5.2 ka, during which time there were five century-scale high and low lake stands. After 5.2 ka, the ISM trended toward drier conditions to the present, with the exception of a pluvial event centered at 0.9 ka. The Paru Co results share similarities with paleoclimate records from across the Tibetan Plateau, suggesting millennial-scale ISM dynamics were expressed coherently. These millennial …