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Antidiabetic effects of combined aqueous fruit extract of Morinda citrifolia and Coccinia indica were evaluated in alloxan induced diabetic rats. The combined aqueous fruit extract of M. citrifolia and C. indica at a concentration of 300 mg/kg body weight/rat/day was orally administered to Alloxan induced diabetic rats for a period of 30 days. The elevated levels of blood glucose in the diabetic rats reverted back to near normal after treatment with the combined aqueous fruit extract of Morinda citrifolia and Coccinia indica. Similarly significant decrease in the levels of plasma insulin elevated to near normal after treatment with fruit extract, suggesting the antihyperglycemic effect of combined aqueous fruit extract of Morinda citrifolia and Coccinia indica.